The peer-reviewed backbone of digital health.

A curated index of 27 peer-reviewed journals shaping evidence in digital medicine, AI in clinical care, telehealth, and biomedical informatics — for clinicians, researchers, builders, and policymakers.

Curated by Daniel Kraft, MD.

27Curated journals
4Editorial categories
14Open-access titles
May 2026Last updated

Digital health moves fast. Evidence still matters.

This curated index highlights the peer-reviewed journals where rigorous work on digital therapeutics, clinical AI, telehealth, wearables, and biomedical informatics is published, debated, and validated. Each entry links directly to the journal's home page.

Use this page to
Find where digital health evidence is published and debated.
Use this page to
Identify journals for submission, peer review, or systematic literature search.
Use this page to
Track research behind AI in medicine, telehealth, wearables, and digital therapeutics.
Where to start

Which journal should you start with?

Not every digital health paper belongs in the same journal. The right venue depends on whether the work is clinical, computational, implementation-focused, policy-oriented, or designed for broad open access. Use this guide as a starting point, then confirm scope, indexing, article types, publication fees, and author instructions directly with each journal.

Highest-prestige digital medicine
Clinical AI & LLMs in medicine
Biomedical informatics methods
Mobile health, wearables & digital biomarkers
Policy, payment & reimbursement

This guide reflects general fit for typical research questions. Journal scope, accepted article types, and editorial focus shift over time — verify current scope and submission requirements at each journal's website before deciding.

01 · Flagship

The peer-reviewed core.

High-impact journals shaping evidence-based digital medicine, AI in clinical care, and biomedical informatics.

Open AccessHigh-Impact

Elsevier · The Lancet Group
Best for: high-visibility, practice-changing clinical trials and large-scale digital health evaluations.

Publishes important, innovative, and practice-changing research connected with digital technology in clinical medicine, public health, and global health — bridging health professionals, technologists, and the wider research community.

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Open AccessNature

Nature Partner Journals
Best for: rigorous clinical and translational digital medicine, including wearables, sensors, and longitudinal data analytics.

An online open-access journal devoted to high-quality peer-reviewed research across all aspects of digital medicine — clinical implementation of digital and mobile technologies, virtual care, novel sensors, and longitudinal data analytics.

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New additionAI in Medicine

NEJM Group · Massachusetts Medical Society
Best for: peer-reviewed clinical AI evaluations, generative AI deployment studies, and AI safety in medicine.

A monthly journal from the NEJM Group dedicated to rigorous, peer-reviewed evaluation of artificial intelligence and machine learning in clinical medicine. Pairs pre-clinical and clinical articles to bridge developers, clinicians, and policymakers.

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New additionInformatics

Oxford University Press · AMIA
Best for: biomedical and health informatics research, EHR studies, and clinical decision support.

AMIA's flagship peer-reviewed journal for biomedical and health informatics. Covers clinical care, clinical research, translational science, implementation science, imaging, education, consumer health, public health, and policy.

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High-ImpactTranslational

Springer Nature
Best for: landmark translational research, including high-impact AI-in-medicine and clinical genomics studies.

A premier translational and clinical journal increasingly central to digital-health and AI-in-medicine research, including landmark generative AI deployment studies and clinical decision support trials.

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New additionHigh-Impact

BMJ Publishing Group
Best for: evidence-based digital interventions, regulatory science, and AI clinical-trial reporting standards.

One of the world's oldest general medical journals, increasingly central to digital health policy, AI clinical trials, and evidence-based digital intervention research. Strong coverage of regulatory science and the implementation of clinical AI.

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02 · Open Access

Free to read, faster to share.

Open-access titles where digital-health research is published without paywalls — built for global access and rapid dissemination.

Open AccessPioneering

JMIR Publications
Best for: high-volume eHealth research, digital interventions, and behavior-change studies needing fast open-access reach.

The pioneering open-access eHealth journal and flagship of JMIR Publications — a leading global digital health journal by quality, visibility, and volume. Focuses on emerging technologies, medical devices, apps, engineering, and informatics for prevention and care.

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Open AccessInterdisciplinary

SAGE Publications
Best for: interdisciplinary digital health research bridging informatics, clinical care, and behavior change.

An interdisciplinary forum bridging informatics, technology, and clinical medicine. Covers eHealth, connected health, telemedicine, wearables, mobile health, genomics, big data, behavior change, and the social and ethical implications of advances in the field.

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Open AccessEquity-Focused

Public Library of Science
Best for: equity-focused digital health, fairness in clinical AI, and global public health applications.

A community-driven journal reflecting the full breadth of digital health research, including social and ethical issues. Strong focus on public health, big-data management, fairness and disparities, patient accessibility, behavior, and precision medicine.

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New additionOpen Access

Frontiers Media
Best for: multidisciplinary digital health, AI ethics and personalization studies, and topical research collections.

A multidisciplinary open-access journal publishing rigorously peer-reviewed research across the digital health spectrum — from AI and big data to ethics and personalization — in service of better prevention, diagnostics, and treatment, anywhere and anytime.

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New additionOpen Access

BMJ Group · BCS
Best for: applied informatics in care delivery, learning health systems research, and front-line practitioner studies.

An international, peer-reviewed, open-access journal focused on how informatics supports improvements in direct health and care service provision, learning health systems, and national policy. Bridges academic and front-line practitioner communities.

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Open AccessHigh-Impact

American Medical Association
Best for: empirical evaluations of clinical AI tools, LLM diagnostic studies, and EHR-integrated AI deployments.

The de facto venue for empirical evaluations of digital health and clinical AI tools — including LLM diagnostic reasoning trials, telehealth equity studies, and EHR-integrated AI deployments. Open access, fast turnaround, high citation velocity.

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03 · AI, Informatics & Methods

Where computation meets medicine.

Journals at the intersection of biomedical informatics, machine learning, digital biomarkers, and clinical decision support.

New additionOpen Access

Cell Press · Elsevier
Best for: AI in oncology, drug development, ophthalmology, and high-impact translational digital medicine.

A premium open-access translational and clinical journal from Cell Press with a dedicated Digital Health collection covering AI in oncology, drug development, mental health, ophthalmology, and metabolic diseases.

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Open AccessMultidisciplinary

Karger Publishers
Best for: sensor-derived biomarkers, validation studies, and connected-device clinical research.

A multidisciplinary open-access journal bridging computer science, engineering, biomedicine, regulatory science, and informatics. Provides and supports access to data, algorithms, and app repositories linked to its published articles.

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New additionEngineering

IEEE Engineering in Medicine & Biology Society
Best for: machine-learning methods, signal processing, and engineering papers on biomedical and connected-device informatics.

Publishes original papers on the technology and methodology of acquiring, transmitting, storing, retrieving, processing, and analyzing biomedical information — including AI, machine learning, signal processing, and connected-device informatics.

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New additionInformatics

Elsevier
Best for: EHR studies, NLP for clinical text, and implementation science behind digital tools in real-world health systems.

Long-running, internationally respected journal covering health and biomedical informatics, decision support, electronic health records, NLP for clinical text, and the implementation science behind digital tools in real-world health systems.

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MethodsEstablished

Elsevier
Best for: AI methods papers, model architectures, validation, and interpretability research in clinical medicine.

A long-running technical journal for AI and machine-learning methods applied to clinical medicine — model architectures, validation methods, interpretability, and real-world medical-domain impact assessments.

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MethodsInformatics

Elsevier
Best for: data standards, ontologies, NLP for clinical text, and computational approaches to biomedical knowledge.

A methods-focused informatics journal covering data standards, ontologies, NLP for clinical text, knowledge representation, and computational approaches to biomedical knowledge. Pairs well with JAMIA on the technical side.

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New additionApplied Informatics

Thieme · AMIA · IMIA · EFMI
Best for: EHR implementation, clinical decision support, and the practical workflow side of health IT.

Official journal of AMIA, IMIA, and EFMI focused on practical clinical informatics. Covers clinical information systems, electronic medical records, physician order entry, clinical decision support, mobile health, and the workflow side of health IT.

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04 · Applied

Care delivery in practice.

Telemedicine, mHealth, and applied digital-care delivery — how the field shows up at the bedside, on the phone, and in the home.

New additionTelehealth

Mary Ann Liebert · American Telemedicine Association
Best for: telehealth implementation, remote patient monitoring, and care delivery in rural and remote settings.

The leading peer-reviewed journal for cutting-edge telemedicine applications, with emphasis on impact on quality, cost effectiveness, and access. Covers home healthcare, RPM, disease management, and care across rural, urban, and extreme settings.

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New additionOpen Access

JMIR Publications
Best for: mobile health apps, wearables, sensors, and consumer health technology research.

A high-impact, peer-reviewed open-access journal focused on health and biomedical apps, smartphone and tablet apps, wearables, sensors, ubiquitous computing, and mobile and ambient assistive technologies for health and wellness.

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Open AccessGlobal

Graphy Publications
Best for: case reports, applied digital healthcare research, and global authorship across the field.

An international peer-reviewed open-access journal devoted to digital healthcare. Publishes original articles, commentary, editorials, reviews, and case reports across the major fields of digital healthcare research and development.

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Hybrid AccessQuarterly

Wolters Kluwer · International Society of Digital Medicine
Best for: applied digital therapeutics, retrieval-augmented generation in care, and clinical implementation of AI tools.

A peer-reviewed quarterly journal of the International Society of Digital Medicine, now published by Wolters Kluwer (Lippincott). Covers AI in medicine, retrieval-augmented generation, digital therapeutics, and the integration of digital tools into clinical practice.

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PolicyImplementation

Project HOPE
Best for: digital therapeutics reimbursement, telehealth policy, FDA SaMD regulation, and AI governance research.

The leading peer-reviewed journal of health policy, economics, and implementation. Where digital therapeutics reimbursement, telehealth policy, FDA SaMD regulation, and AI governance research lands. Essential for the policy and implementation side of digital health.

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New additionOpen Access

Wiley · University of Michigan
Best for: learning health systems research, real-world evidence, and continuous-improvement studies in care delivery.

An international, open-access, peer-reviewed journal advancing the interdisciplinary field of learning health systems — promoting research, scholarship, and dialogue on continuous improvement in healthcare through cycles of inclusive discovery and implementation.

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New additionCare Delivery

NEJM Group · Massachusetts Medical Society
Best for: health system innovation, value-based care models, and operational case studies from care-delivery leaders.

A peer-reviewed digital journal from the NEJM Group focused on innovations in healthcare delivery, value-based care, patient engagement, organizational leadership, and the new marketplace of healthcare. Pairs research with health-system case studies and in-depth analyses.

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New additionOpen Access

Elsevier · Mayo Clinic
Best for: implementation, validation, and translation of digital health solutions including VR/AR, wearables, and platform care.

An open-access, peer-reviewed journal sponsored by Mayo Clinic and published by Elsevier. Focuses on translation, implementation, adaptation, and validation of digital health solutions — including AI in medicine, virtual and extended reality, wearables, mobile technology, and platform care.

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Frequently asked

Questions readers ask.

What is the leading peer-reviewed journal in digital health?
The Lancet Digital Health, npj Digital Medicine, NEJM AI, JAMIA, JMIR, and IEEE Journal of Biomedical and Health Informatics are among the most visible and influential peer-reviewed venues for digital health, AI in medicine, and biomedical informatics. Nature Medicine and The BMJ also carry highly cited digital health and AI-in-medicine research.
Are there open-access journals for digital health research?
Yes. PLOS Digital Health, JMIR, Frontiers in Digital Health, Digital Health (SAGE), JAMA Network Open, Cell Reports Medicine, BMJ Health and Care Informatics, JMIR mHealth and uHealth, Learning Health Systems, and Mayo Clinic Proceedings: Digital Health all publish digital-health research under open-access licenses. npj Digital Medicine is also fully open access.
Where do AI in medicine papers get published?
NEJM AI, npj Digital Medicine, JAMIA, Cell Reports Medicine, and IEEE Journal of Biomedical and Health Informatics are widely used venues for AI-in-medicine research. International Journal of Medical Informatics and Artificial Intelligence in Medicine also publish substantial AI work, and JAMA Network Open hosts a large volume of clinical AI evaluations.
How do I search digital-health literature systematically?
Use PubMed for biomedical literature searches and ClinicalTrials.gov for active and completed clinical studies. Both are NIH-maintained and indexed by Google Scholar. For preprint research, medRxiv covers medical and health sciences, while arXiv (cs.LG and q-bio sections) covers most machine-learning-in-medicine work.
What is the difference between npj Digital Medicine and Digital Medicine?
npj Digital Medicine is a Nature Publishing peer-reviewed journal launched in 2018, focused on rigorous clinical and translational digital-medicine research. Digital Medicine (published by Wolters Kluwer / Lippincott) is the journal of the International Society of Digital Medicine and addresses applied digital therapeutics and clinical implementation.
Are these journals indexed in PubMed?
Many of the journals listed are indexed in PubMed, MEDLINE, or both. Indexing status changes over time and may vary by journal. Users should confirm current indexing status on PubMed, the NLM Catalog, or the journal's author instructions before submission.
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Editorial methodology

How this list is curated.

Journals are selected for editorial relevance, not impact factor alone. Inclusion criteria include: peer-review process, sustained publication of digital health, AI in medicine, informatics, or telehealth research, recognition by the field's editorial community, and the practical value of the journal as a destination for readers, authors, or reviewers working in digital health.

The index is reviewed and refreshed at least twice yearly. Last full editorial review: May 2026. We weigh signal over breadth — the goal is a curated set readers can trust, not a comprehensive directory. Indexing status (PubMed, MEDLINE, Scopus) changes over time; verify directly at each journal before submitting.

Have a journal we should add or remove? Email hello@digital.health with a brief case for inclusion. We weigh editorial focus, peer-review rigor, publication volume, and complementarity with the existing index.

Last reviewed and updated May 8, 2026. Curated by Digital.Health. Suggest a journal we should add: hello@digital.health.

Complete index of digital health and AI journals

Digital.Health curates 27 essential peer-reviewed journals across four editorial categories — Flagship, Open Access, AI & Methods (Informatics), and Applied — plus search databases and preprint servers for a total of 31 resources. The index includes a decision-support guide that maps research questions to recommended publication venues. Last updated May 8, 2026.

Flagship journals (6)

  • The Lancet Digital Health — Elsevier · The Lancet Group. Practice-changing research connecting digital technology with clinical medicine, public health, and global health.
  • npj Digital Medicine — Nature Partner Journals. Open-access journal across all aspects of digital medicine including virtual care, novel sensors, and longitudinal data analytics.
  • NEJM AI — NEJM Group. Monthly journal dedicated to peer-reviewed evaluation of AI and machine learning in clinical medicine.
  • Journal of the American Medical Informatics Association (JAMIA) — Oxford University Press · AMIA. Flagship journal for biomedical and health informatics.
  • Nature Medicine — Springer Nature. Premier translational and clinical journal central to digital-health and AI-in-medicine research.
  • The BMJ — BMJ Publishing Group. General medical journal covering digital health policy, AI clinical trials, and evidence-based digital interventions.

Open Access journals (6)

  • Journal of Medical Internet Research (JMIR) — JMIR Publications. Pioneering open-access eHealth journal.
  • Digital Health (SAGE) — SAGE Publications. Interdisciplinary forum for eHealth, telemedicine, wearables, and mobile health.
  • PLOS Digital Health — Public Library of Science. Community-driven journal with strong focus on fairness, disparities, and precision medicine.
  • Frontiers in Digital Health — Frontiers Media. Multidisciplinary open-access journal across the digital health spectrum.
  • BMJ Health & Care Informatics — BMJ Group · BCS. Informatics for direct care provision, learning health systems, and national policy.
  • JAMA Network Open — American Medical Association. Widely used venue for empirical evaluations of digital health and clinical AI tools.

AI, Informatics & Methods journals (7)

  • Cell Reports Medicine — Cell Press · Elsevier. Open-access translational journal with a dedicated Digital Health collection.
  • Digital Biomarkers — Karger Publishers. Multidisciplinary journal bridging computer science, engineering, and biomedicine.
  • IEEE Journal of Biomedical and Health Informatics — IEEE EMBS. AI, machine learning, and signal processing for biomedical information.
  • International Journal of Medical Informatics — Elsevier. Health and biomedical informatics, decision support, and EHRs.
  • Artificial Intelligence in Medicine — Elsevier. Technical journal for AI and machine-learning methods in clinical medicine.
  • Journal of Biomedical Informatics — Elsevier. Methods-focused informatics covering data standards, ontologies, and NLP.
  • Applied Clinical Informatics — Thieme · AMIA, IMIA, EFMI. Practical clinical informatics covering EHR implementation, clinical decision support, and health IT workflows.

Applied journals (8)

  • Telemedicine and e-Health — Mary Ann Liebert · ATA. Leading peer-reviewed telemedicine journal.
  • JMIR mHealth and uHealth — JMIR Publications. Health and biomedical apps, wearables, sensors, and ambient assistive technologies.
  • International Journal of Digital Healthcare (IJDH) — Graphy Publications. International peer-reviewed open-access journal devoted to digital healthcare.
  • Digital Medicine — Wolters Kluwer · Lippincott. Quarterly journal of the International Society of Digital Medicine.
  • Health Affairs — Project HOPE. Leading journal of health policy, economics, and implementation.
  • Learning Health Systems — Wiley · University of Michigan. Open-access journal advancing learning health systems research and continuous improvement in care.
  • NEJM Catalyst Innovations in Care Delivery — NEJM Group. Peer-reviewed journal on healthcare delivery innovation, value-based care, and operational case studies.
  • Mayo Clinic Proceedings: Digital Health — Elsevier · Mayo Clinic. Open-access journal focused on translation, implementation, and validation of digital health solutions.

Search the literature (2)

  • PubMed — NIH/NLM database of biomedical literature.
  • ClinicalTrials.gov — NIH registry of publicly and privately funded clinical studies.

Preprints (2)

  • medRxiv — preprint server for medical and health-sciences research.
  • arXiv (cs.LG / q-bio) — preprint server for machine-learning-in-medicine and computational biology.